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Cytokine will publish studies that report on the molecular biology, signal transduction, genetics, biochemistry, immunology, genome-wide association, pathobiology, diagnostic, clinical, and therapeutic applications of all known and emerging cytokines, cytotoxins, interferons, chemokines, …. View full aims & scope


Cytokine. Cytokines are a broad and loose category of small proteins (~5–25 kDa [1]) important in cell signaling. Due to their size, cytokines cannot cross the lipid bilayer of cells to enter the cytoplasm and therefore typically exert their functions by interacting with specific cytokine receptors on the target cell surface.


Therapeutic modulation of cytokine expression can help the "good" cytokines to generate or quench the immune system and block the "bad" cytokines to prevent damaging inflammatory events. However, care must be exercised, as some antibody therapeutics can cause "ugly" cytokine release which can be deadly. Well-designed toxicology studies should ...
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Cytokines include different types of proteins that tell immune cells where to go and what to do to keep your immune system functioning correctly. Chemokines: Chemokines direct immune cells toward places in your body where they can fight infection. Interferons: Interferons signal cells to put up their defenses against viruses invading your body.


Cytokines are molecules that allow your cells to talk to each other, and are crucial for healthy immune system function. Too many cytokines, however, can have a negative effect and result in what ...


Editor’s Choice articles are based on recommendations by the scientific editors of MDPI journals from around the world. Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area.


Cytokines: Introduction. In order to mount and coordinate an effective immune response, a mechanism by which lymphocytes, inflammatory cells and haematopoietic cells can communicate with each other is required. Cytokines perform this function. Cytokines are a large, diverse family of small proteins or glycoproteins (usually smaller than 30 kDa).